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HARS1
Histidyl-tRNA synthetase 1HARS, HisRS, USH3B
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Top validated antibodies |
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| Atlas Antibodies |  HPA036539 |
Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-112441 |
Polyclonal |
WB
EL
IP
IHC
OA
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| antibodies-online | ABIN394952 |
Monoclonal |
WB
EL
ICC
IHC
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| Acris Antibodies GmbH | AP52002PU-N |
Polyclonal |
WB
EL
IHC
FC
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| Abnova Corporation | PAB2968 |
2 references | Polyclonal |
WB
IHC
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