Tissue expression
Cell line expression
Protein structure
TSPAN6
Tetraspanin 6T245, TM4SF6, TSPAN-6
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]
Top validated antibodies |
|||||
LSBio | LS-C376955 | Polyclonal |
WB
EL
IHC
|
||
Cusabio Biotech Co., Ltd | CSB-PA025164LA01HU | Polyclonal |
WB
EL
ICC
IHC |
||
Aviva Systems Biology | OAAB05816 | Polyclonal |
WB
EL
FC
|
||
antibodies-online | ABIN405740 | 1 references | Polyclonal |
WB
|
|
Atlas Antibodies | HPA004109 | Polyclonal |
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider