Tissue expression
Cell line expression
Protein structure
RUFY3
RUN and FYVE domain containing 3KIAA0871, RIPx, Singar1, ZFYVE30
This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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Atlas Antibodies | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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