Tissue expression
Cell line expression
Protein structure
BAK1
BCL2 antagonist/killer 1BAK, BCL2L7, CDN1
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | MA5-32111 | 2 references | Monoclonal |
WB
ICC
IHC
FC
OA
|
|
Novus Biologicals | NBP2-67460 | 1 references | Monoclonal |
WB
ICC
IP
IHC
FC
|
|
Proteintech Group | 14673-1-AP | 35 references | Polyclonal |
WB
EL
IHC
|
|
Boster Biological Technology | M01163-1 | 2 references | Monoclonal |
WB
ICC
IHC
FC |
|
NSJ Bioreagents | R32246 | Polyclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider