Tissue expression
Cell line expression
Protein structure
BAK1
BCL2 antagonist/killer 1BAK, BCL2L7, CDN1
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
2 references | Monoclonal |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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Proteintech Group | ![]() |
35 references | Polyclonal |
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Boster Biological Technology | ![]() |
2 references | Monoclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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