Tissue expression
Cell line expression
Protein structure
SNX13
Sorting nexin 13KIAA0713, RGS-PX1
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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St John's Laboratory | ![]() |
Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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