Tissue expression
Cell line expression
Protein structure
LLGL2
LLGL scribble cell polarity complex component 2HGL, Hugl-2
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
7 references | Monoclonal |
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Abnova Corporation | ![]() |
6 references | Monoclonal |
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antibodies-online | ![]() |
6 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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LSBio | ![]() |
Monoclonal |
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