Tissue expression
Cell line expression
Protein structure
CLCN4
Chloride voltage-gated channel 4ClC-4, CLC4
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012]
Top validated antibodies |
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antibodies-online | ABIN358900 | 5 references | Polyclonal |
WB
EL
ICC
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Invitrogen Antibodies | PA5-13348 | 1 references | Polyclonal |
WB
ICC
IHC
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Abnova Corporation | PAB4423 | 3 references | Polyclonal |
WB
ICC |
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NovoPro Bioscience Inc. | 135908 | Polyclonal |
WB
EL
ICC
IHC |
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Abgent | AP6329f | Polyclonal |
WB
ICC
IHC
|
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