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Protein structure
PKP1
Plakophilin 1B6P
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Top validated antibodies |
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| Invitrogen Antibodies |  32-5700 |
5 references | Monoclonal |
WB
ICC
IP
OA
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| Atlas Antibodies | HPA027221 |
2 references | Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NBP1-90042 |
1 references | Polyclonal |
WB
ICC
IHC
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| NSJ Bioreagents | V3392 |
2 references | Monoclonal |
WB
ICC
OA
|
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| OriGene | BM5110 |
Monoclonal |
WB
EL
ICC
IHC
|
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