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Protein structure
CD82
CD82 moleculeIA4, KAI1, R2, ST6, TSPAN27
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| OriGene |  AM26701PU-N |
1 references | Monoclonal |
WB
ICC
IP
IHC
FC
FA
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| Novus Biologicals | NBP1-76775 |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| Biorbyt | orb257047 |
Monoclonal |
WB
ICC
IP
IHC
FC
FA
|
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| Invitrogen Antibodies | PA5-13228 |
2 references | Polyclonal |
WB
IHC
FC
|
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| Abnova Corporation | PAB4830 |
3 references | Polyclonal |
WB
IHC
FC
|
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