Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunitCDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Top validated antibodies |
|||||
| Proteintech Group |  20551-1-AP |
3 references | Polyclonal |
WB
EL
IP
IHC
|
|
| Invitrogen Antibodies | 20551-1-AP |
Polyclonal |
WB
IP
IHC
OA
|
||
| Acris Antibodies GmbH | AM08331PU-M |
2 references | Monoclonal |
WB
ICC
IP
IHC
|
|
| Novus Biologicals | NB100-60942 |
1 references | Polyclonal |
WB
EL
IHC
|
|
| NovoPro Bioscience Inc. | 115841 |
Polyclonal |
WB
EL
IP
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider