TIMM13

This gene encodes a member of the evolutionarily conserved TIMM (translocase of inner mitochondrial membrane) family of proteins that function as chaperones in the import of proteins from the cytoplasm into the mitochondrial inner membrane. Proteins of this family play a role in collecting substrate proteins from the translocase of the outer mitochondrial membrane (TOM) complex and delivering them to either the sorting and assembly machinery in the outer mitochondrial membrane (SAM) complex or the TIMM22 complex in the inner mitochondrial membrane. The encoded protein and the translocase of mitochondrial inner membrane 8a protein form a 70 kDa complex in the intermembrane space. [provided by RefSeq, Jul 2013]

Description

Translocase of inner mitochondrial membrane 13

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli fibrillar center, Mitochondria

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

19 (2425625 - 2427586)

Ensembl ID

ENSG00000099800  (ver. 103.38)

Orthologs

Mouse Timm13: ENSMUSG00000020219

UniProt

Q9Y5L4

neXtProt

NX_Q9Y5L4

Human splice variants
Mouse splice variants

Protein structure