Tissue expression
Cell line expression
Protein structure
ABHD12
Abhydrolase domain containing 12, lysophospholipaseABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2011]
Top validated antibodies |
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antibodies-online | ABIN2842551 | 1 references | Polyclonal |
WB
IHC
FC
|
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NSJ Bioreagents | F51417 | Polyclonal (Antigen purified) |
WB
EL
IHC
FC |
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Abgent | AP8904a | Polyclonal |
WB
IHC
FC
|
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GeneTex | GTX80950 | Polyclonal |
WB
IHC
FC
|
||
Invitrogen Antibodies | PA5-72593 | Polyclonal |
WB
IHC
FC
|
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider