Tissue expressionAmygdalaBasal gangliaCerebellumCerebral cortexChoroid plexusHippocampal formationHypothalamusMedulla oblongataMidbrainOlfactory bulbPonsSpinal cordThalamusWhite matterRetinaAdrenal glandParathyroid glandPituitary glandThyroid glandLungEsophagusSalivary glandTongueColonDuodenumRectumSmall intestineStomachGallbladderLiverPancreasKidneyUrinary bladderEpididymisProstateSeminal vesicleTestisBreastCervixEndometriumFallopian tubeOvaryPlacentaVaginaHeart muscleSkeletal muscleSmooth muscleAdipose tissueSkinAppendixBone marrowLymph nodeSpleenThymusTonsil0102030405060
Cell line expressionAF22GAMGSH-SY5YU-138 MGU-251 MGU-87 MGHTCEpiHTERT-RPE1OE19CACO-2Hep G2CAPAN-2HEK 293NTERA-2RPTEC TERT1RT4PC-3SuSaA-431HaCaTSK-MEL-30WM-115A549HBEC3-KTSCLC-21HAN3-CABEWOEFO-21HeLaHTERT-HME1MCF7SiHaSK-BR-3T-47dHUVEC TERT2TIMEHSkMCASC diffASC TERT1BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VFHDF/TERT166HBF TERT88HHSteCLHCN-M2RH-30U-2 OSU-2197DaudiHDLM-2HTEC/SVTERT24-BJURKATKarpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698HAP1HELHL-60HMC-1K-562NB-4THP-1U-937020406080
Protein structure

STK4

Serine/threonine kinase 4
KRS2, MST1, YSK3 
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008]
More gene data

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                        518 antibodies from 44 providers.

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                        Antibody
                        Refs
                        Type
                        WB
                        EL
                        ICC
                        IP
                        IHC
                        FC
                        Proteintech Group
                        4 antibodies
                        Invitrogen Antibodies
                        49 antibodies
                        Novus Biologicals
                        6 antibodies
                        Atlas Antibodies
                        1 antibody
                        Abnova Corporation
                        9 antibodies
                        antibodies-online
                        128 antibodies
                        GeneTex
                        7 antibodies
                        OriGene
                        2 antibodies
                        NovoPro Bioscience Inc.
                        10 antibodies
                        St John's Laboratory
                        9 antibodies
                        Biorbyt
                        32 antibodies
                        Antibodies.com
                        9 antibodies
                        Abcepta
                        6 antibodies
                        Aviva Systems Biology
                        4 antibodies
                        FineTest Biotech
                        1 antibody
                        R&D Systems
                        1 antibody
                        Cell Signaling Technology, Inc
                        4 antibodies
                        Signalway Antibody LLC
                        1 antibody
                        Cusabio Biotech Co., Ltd
                        7 antibodies
                        Bethyl Laboratories
                        2 antibodies
                        Affinity Biosciences
                        1 antibody
                        Acris Antibodies GmbH
                        6 antibodies
                        NSJ Bioreagents
                        1 antibody
                        Sino Biological Inc.
                        5 antibodies
                        Boster Biological Technology
                        1 antibody
                        RabMAbs
                        5 antibodies
                        ProSci
                        2 antibodies
                        HUABIO Research
                        1 antibody
                        MilliporeSigma / Merck KGaA
                        2 antibodies
                        MyBioSource
                        6 antibodies
                        ABEOMICS Inc.
                        2 antibodies
                        Creative Biolabs
                        16 antibodies
                        Arigo
                        1 antibody
                        Bioworld Technology, Inc
                        1 antibody
                        United States Biological
                        45 antibodies
                        Abbexa
                        18 antibodies
                        Leading Biology
                        4 antibodies
                        Abiocode, Inc.
                        1 antibody
                        EMD Millipore
                        1 antibody
                        RayBiotech, Inc.
                        1 antibody
                        Creative Diagnostics
                        2 antibodies
                        MedChemExpress LLC
                        1 antibody