Tissue expression
Cell line expression
Protein structure
PLS3
Plastin 3T-plastin
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
5 references | Polyclonal |
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GeneTex | ![]() |
2 references | Polyclonal |
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Proteintech Group | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Monoclonal |
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antibodies-online | ![]() |
Polyclonal |
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