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Protein structure
SGCG
Sarcoglycan gammaA4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
Top validated antibodies |
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| Proteintech Group |  18102-1-AP |
5 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 18102-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| LSBio | LS-C802966 |
Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NBP2-66859 |
Monoclonal |
WB
IP
IHC
ChIP
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| NovoPro Bioscience Inc. | 115163 |
Polyclonal |
WB
EL
IP
IHC
|
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