Tissue expression
Cell line expression
Protein structure
STX1A
Syntaxin 1AHPC-1, p35-1, STX1
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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antibodies-online | ABIN955037 | 6 references | Polyclonal |
WB
IHC
FC
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Invitrogen Antibodies | MA5-17612 | 5 references | Monoclonal |
WB
IHC
OA
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GeneTex | GTX113559 | 2 references | Polyclonal |
WB
ICC
IHC
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LSBio | LS-C199629 | Polyclonal |
WB
EL
ICC
IHC |
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Enzo Life Sciences | ADI-VAP-SV064-E | 4 references | Polyclonal |
WB
ICC
IP
IHC |
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Supportive data in Antibodypedia
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Recommended by provider