Tissue expression
Cell line expression
Protein structure
PLEKHA1
Pleckstrin homology domain containing A1TAPP1
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Sep 2010]
Top validated antibodies |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Atlas Antibodies | ![]() |
Polyclonal |
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