Tissue expression
Cell line expression
Protein structure
DSE
Dermatan sulfate epimeraseDS-Epi1, DSEPI, SART2
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016]
Top validated antibodies |
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antibodies-online | ABIN396720 | 5 references | Monoclonal |
WB
EL |
|
Proteintech Group | 10452-1-AP | 1 references | Polyclonal |
EL
IHC |
|
NovoPro Bioscience Inc. | 107242 | Monoclonal |
WB
EL
IHC
|
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Cusabio Biotech Co., Ltd | CSB-PA890925LA01HU | Polyclonal |
EL
ICC
IHC
|
||
FineTest Biotech | FNab02543 | Monoclonal |
WB
EL
IHC
|
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