Tissue expression
Cell line expression
Protein structure
SASH1
SAM and SH3 domain containing 1dJ323M4.1, KIAA0790, SH3D6A
This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016]
Top validated antibodies |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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