Tissue expression
Cell line expression
Protein structure
RNF8
Ring finger protein 8KIAA0646
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Top validated antibodies |
|||||
Proteintech Group | 14112-1-AP | 20 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 14112-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
||
NovoPro Bioscience Inc. | 114764 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
antibodies-online | ABIN954577 | 6 references | Polyclonal |
WB
FC |
|
Novus Biologicals | H00009025-B01P | 4 references | Polyclonal |
WB
ICC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider