Tissue expression
Cell line expression
Protein structure
GHR
Growth hormone receptorGHBP
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Top validated antibodies |
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Proteintech Group | 20713-1-AP | 4 references | Polyclonal |
WB
EL
ICC
IHC |
|
Novus Biologicals | AF1210 | 2 references | Polyclonal |
WB
IHC
FC
BN |
|
R&D Systems | AF1210 | 2 references | Polyclonal |
WB
IHC
FC
BN |
|
antibodies-online | ABIN671481 | 6 references | Polyclonal |
WB
ICC
IHC
FC |
|
Boster Biological Technology | A00698 | Polyclonal |
WB
EL
ICC
FC |
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