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Cell line expression
Protein structure
SPARC
Secreted protein acidic and cysteine richBM-40, ON, ONT
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015]
Top validated antibodies |
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| R&D Systems |  AF942 |
12 references | Polyclonal |
WB
ICC
IHC
FC
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| Novus Biologicals | AF941 |
9 references | Polyclonal |
WB
EL
IHC
FC
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| Proteintech Group | 15274-1-AP |
39 references | Polyclonal |
WB
EL
IHC
|
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| GeneTex | GTX19528 |
3 references | Monoclonal |
WB
EL
IHC
RA
|
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| Invitrogen Antibodies | 33-5500 |
28 references | Monoclonal |
WB
EL
IHC
FC
OA
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