PDC

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Description

Phosducin

Tissue specificity

Tissue enriched (retina)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

1 (186443566 - 186461114)

Ensembl ID

ENSG00000116703  (ver. 103.38)

Orthologs

Mouse Pdc: ENSMUSG00000006007

UniProt

P20941

neXtProt

NX_P20941

Human splice variants
Mouse splice variants

Protein structure