Tissue expression
Cell line expression
Protein structure
PRDM2
PR/SET domain 2HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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NSJ Bioreagents | RQ8171 | Polyclonal |
WB
EL
ICC
IHC
FC
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Biorbyt | orb1743904 | Polyclonal |
WB
EL
ICC
IHC
FC
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antibodies-online | ABIN2838021 | 2 references | Monoclonal |
WB
IHC
ChIP
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Abgent | AM1194A | 2 references | Monoclonal |
WB
ChIP |
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Abnova Corporation | MAB1151 | 3 references | Monoclonal |
WB
IP |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider