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Protein structure
KDM5B
Lysine demethylase 5BCT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Top validated antibodies |
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| Novus Biologicals |  H00010765-M02 |
4 references | Monoclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN395143 |
7 references | Monoclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | H00010765-M02 |
3 references | Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | MA5-24626 |
1 references | Monoclonal |
WB
ICC
IHC
OA
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| Biorbyt | orb101871 |
Polyclonal |
WB
EL
ICC
IHC
FC
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