Tissue expression
Cell line expression
Protein structure
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyaseHL
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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Atlas Antibodies | ![]() |
1 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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