Tissue expression
Cell line expression
Protein structure
PKD2
Polycystin 2, transient receptor potential cation channelPc-2, PC2, PKD4, TRPP2
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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Proteintech Group | ![]() |
4 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
5 references | Polyclonal |
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