Tissue expression
Cell line expression
Protein structure
CXCR4
C-X-C motif chemokine receptor 4CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX22074 | 5 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Novus Biologicals | NBP1-77067 | 4 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | PA3-305 | 13 references | Polyclonal |
WB
ICC
IHC
FC
OA
|
|
R&D Systems | MAB21651-100 | 25 references | Monoclonal |
ICC
IHC
FC
BN |
|
Proteintech Group | 11073-2-AP | 46 references | Polyclonal |
WB
EL
IP
IHC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider