H2BW1

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility. [provided by RefSeq, Oct 2015]

Description

H2B.W histone 1

Tissue specificity

Not detected

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X (104011147 - 104013687)

Ensembl ID

ENSG00000123569  (ver. 103.38)

Orthologs

-

UniProt

Q7Z2G1

neXtProt

NX_Q7Z2G1

Human splice variants

Protein structure