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Cell line expression
Protein structure
C4BPB
Complement component 4 binding protein betaC4BP
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  15837-1-AP |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | H00000725-M01 |
1 references | Monoclonal |
WB
EL
IP
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| antibodies-online | ABIN513876 |
1 references | Monoclonal |
WB
EL
IP
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| Invitrogen Antibodies | 15837-1-AP |
Polyclonal |
WB
ICC
IHC
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| FineTest Biotech | FNab01114 |
Polyclonal |
WB
EL
ICC
IHC
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