Tissue expression
Cell line expression
Protein structure
PSMB2
Proteasome 20S subunit beta 2HC7-I
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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Proteintech Group | 15154-1-AP | 3 references | Polyclonal |
WB
EL
ICC
IHC |
|
Novus Biologicals | NBP1-92294 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
NSJ Bioreagents | RQ8148 | Polyclonal |
WB
EL
ICC
FC |
||
St John's Laboratory | STJ115589 | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
||
Invitrogen Antibodies | PA5-89333 | Polyclonal |
WB
ICC
IP
IHC |
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Supportive data in Antibodypedia
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Recommended by provider