Tissue expression
Cell line expression
Protein structure
PROZ
Protein Z, vitamin K dependent plasma glycoproteinPZ
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Top validated antibodies |
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Atlas Antibodies | ![]() |
Polyclonal |
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LSBio | ![]() |
Monoclonal |
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OriGene | ![]() |
Monoclonal |
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antibodies-online | ![]() |
2 references | Monoclonal |
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Acris Antibodies GmbH | ![]() |
Monoclonal |
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