Tissue expression
Cell line expression
Protein structure
BCL2L12
BCL2 like 12This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Top validated antibodies |
|||||
Invitrogen Antibodies | MA5-34871 | Monoclonal |
WB
ICC
IHC
FC |
||
Biorbyt | orb1727099 | Monoclonal |
WB
ICC
IP
IHC
FC
|
||
Proteintech Group | 21969-1-AP | Polyclonal |
WB
EL
ICC
IHC |
||
NovoPro Bioscience Inc. | 108424 | Polyclonal |
WB
EL
ICC
IHC |
||
HUABIO Research | ET7110-02 | Monoclonal |
WB
ICC
IHC
FC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider