Tissue expression
Cell line expression
Protein structure

AVPR2

Arginine vasopressin receptor 2
DIR, DIR3, V2R 
This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing. [provided by RefSeq, Jul 2008]
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352 antibodies from 32 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Biorbyt
65 antibodies
antibodies-online
105 antibodies
St John's Laboratory
4 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
OriGene
7 antibodies
NovoPro Bioscience Inc.
5 antibodies
GeneTex
5 antibodies
Aviva Systems Biology
3 antibodies
Affinity Biosciences
1 antibody
Invitrogen Antibodies
11 antibodies
Novus Biologicals
5 antibodies
Acris Antibodies GmbH
4 antibodies
Bioworld Technology, Inc
1 antibody
Enzo Life Sciences
1 antibody
Abbkine Scientific Co.Ltd.
2 antibodies
Abnova Corporation
4 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
Abbexa
8 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
EMD Millipore
3 antibodies
Everest Biotech
1 antibody
United States Biological
26 antibodies
Creative Diagnostics
4 antibodies
Leading Biology
4 antibodies
Abgent
3 antibodies
GenWay
2 antibodies
RayBiotech, Inc.
2 antibodies
MyBioSource
1 antibody
ProSci
1 antibody