Tissue expression
Cell line expression
Protein structure
CDKN1C
Cyclin dependent kinase inhibitor 1CBWCR, BWS, KIP2, P57
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Top validated antibodies |
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Invitrogen Antibodies | MA5-11309 | 26 references | Monoclonal |
WB
IP
IHC
FC
OA
|
|
NSJ Bioreagents | V2439 | 1 references | Monoclonal |
WB
ICC
IHC
FC
OA
|
|
Atlas Antibodies | HPA002924 | Polyclonal |
WB
ICC
IHC
|
||
GeneTex | GTX31859 | 1 references | Polyclonal |
WB
EL
ICC
|
|
Novus Biologicals | NBP1-89917 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider