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Protein structure
CDKN1C
Cyclin dependent kinase inhibitor 1CBWCR, BWS, KIP2, P57
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-11309 |
26 references | Monoclonal |
WB
IP
IHC
FC
OA
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| LSBio | LS-C199385 |
Polyclonal |
WB
EL
ICC
IHC
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| NSJ Bioreagents | V2439 |
1 references | Monoclonal |
WB
ICC
IHC
FC
OA
|
|
| Proteintech Group | 23317-1-AP |
6 references | Polyclonal |
WB
EL
IHC
|
|
| GeneTex | GTX31859 |
1 references | Polyclonal |
WB
EL
ICC
|
|
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