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Protein structure
ATP6V1E1
ATPase H+ transporting V1 subunit E1ATP6E, ATP6E2, ATP6V1E, P31, Vma4
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-29899 |
4 references | Polyclonal |
WB
ICC
IHC
OA
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| Proteintech Group | 15280-1-AP |
7 references | Polyclonal |
WB
EL
IP
IHC
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| Novus Biologicals | H00000529-M02 |
1 references | Monoclonal |
WB
EL
ICC
PLA
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| LSBio | LS-B12229 |
Monoclonal |
WB
EL
ICC
IHC
|
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| Atlas Antibodies | HPA029196 |
1 references | Polyclonal |
WB
ICC
IHC
|
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