Tissue expression
Cell line expression
Protein structure
MDFIC
MyoD family inhibitor domain containingHIC, MDFIC1
This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Aviva Systems Biology | ![]() |
Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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