Tissue expression
Cell line expression
Protein structure
LCP1
Lymphocyte cytosolic protein 1CP64, L-PLASTIN, LC64P, PLS2
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
7 references | Polyclonal |
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Boster Biological Technology | ![]() |
1 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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GeneTex | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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