Tissue expressionAmygdalaBasal gangliaCerebellumCerebral cortexChoroid plexusHippocampal formationHypothalamusMedulla oblongataMidbrainOlfactory bulbPonsSpinal cordThalamusWhite matterRetinaAdrenal glandParathyroid glandPituitary glandThyroid glandLungEsophagusSalivary glandTongueColonDuodenumRectumSmall intestineStomachGallbladderLiverPancreasKidneyUrinary bladderEpididymisProstateSeminal vesicleTestisBreastCervixEndometriumFallopian tubeOvaryPlacentaVaginaHeart muscleSkeletal muscleSmooth muscleAdipose tissueSkinAppendixBone marrowLymph nodeSpleenThymusTonsil010203040506070
Cell line expressionAF22GAMGSH-SY5YU-138 MGU-251 MGU-87 MGHTCEpiHTERT-RPE1OE19CACO-2Hep G2CAPAN-2HEK 293NTERA-2RPTEC TERT1RT4PC-3SuSaA-431HaCaTSK-MEL-30WM-115A549HBEC3-KTSCLC-21HAN3-CABEWOEFO-21HeLaHTERT-HME1MCF7SiHaSK-BR-3T-47dHUVEC TERT2TIMEHSkMCASC diffASC TERT1BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VFHDF/TERT166HBF TERT88HHSteCLHCN-M2RH-30U-2 OSU-2197DaudiHDLM-2HTEC/SVTERT24-BJURKATKarpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698HAP1HELHL-60HMC-1K-562NB-4THP-1U-937020406080100120
Protein structure

FPGS

Folylpolyglutamate synthase
 
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
More gene data

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                        164 antibodies from 24 providers.

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                        Antibody
                        Refs
                        Type
                        WB
                        EL
                        ICC
                        IP
                        IHC
                        FC
                        LS-C166246Polyclonal
                        LS-C680494Polyclonal
                        Aviva Systems Biology
                        2 antibodies
                        OAAB04098Polyclonal
                        ARP63438_P050Polyclonal
                        antibodies-online
                        52 antibodies
                        ABIN2437051Polyclonal
                        ABIN2841146Polyclonal
                        NovoPro Bioscience Inc.
                        1 antibody
                        138299Polyclonal
                        NSJ Bioreagents
                        1 antibody
                        F54904Polyclonal
                        Invitrogen Antibodies
                        7 antibodies
                        PA5-72507Polyclonal
                        PA5-98338Polyclonal
                        GeneTex
                        1 antibody
                        GTX1035162Polyclonal
                        ProSci
                        1 antibody
                        62-566Polyclonal
                        Cusabio Biotech Co., Ltd
                        4 antibodies
                        CSB-PA23719A0RbPolyclonal
                        CSB-PA23719B0RbPolyclonal
                        RabMAbs
                        1 antibody
                        T1892Polyclonal
                        Acris Antibodies GmbH
                        5 antibodies
                        AP15565PU-MPolyclonal
                        AP15565PU-NPolyclonal
                        OriGene
                        4 antibodies
                        AP15565PU-MPolyclonal
                        AP15565PU-NPolyclonal
                        Arigo
                        2 antibodies
                        ARG53054Polyclonal
                        ARG53055Polyclonal
                        Novus Biologicals
                        2 antibodies
                        NBP2-16526Polyclonal
                        NBP2-48965Polyclonal
                        MyBioSource
                        2 antibodies
                        MBS9214786Polyclonal
                        MBS301814Polyclonal
                        Abnova Corporation
                        2 antibodies
                        PAB14801Polyclonal
                        H00002356-A01Polyclonal
                        United States Biological
                        12 antibodies
                        F6065-20Polyclonal
                        F6065-20-ML405Polyclonal
                        Spring Bioscience
                        4 antibodies
                        E18340Polyclonal
                        E18341Polyclonal
                        Creative Biolabs
                        6 antibodies
                        MOB-2389z-F(E)Monoclonal
                        MOB-2389z-S(P)Monoclonal
                        bs-13196RPolyclonal
                        bs-13196R-BiotinPolyclonal
                        Antibodies.com
                        1 antibody
                        A308017Monoclonal
                        Atlas Antibodies
                        1 antibody
                        HPA050488Polyclonal
                        Leading Biology
                        1 antibody
                        AMM04611GPolyclonal
                        Creative Diagnostics
                        4 antibodies
                        DCABH-7860Polyclonal
                        DPAB-DC1119Polyclonal