Tissue expression
Cell line expression
Protein structure
LOXL4
Lysyl oxidase like 4FLJ21889, LOXC
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
3 references | Monoclonal |
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antibodies-online | ![]() |
2 references | Polyclonal |
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Enzo Life Sciences | ![]() |
2 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
2 references | Polyclonal |
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