CRABP2

This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

Description

Cellular retinoic acid binding protein 2

Tissue specificity

Group enriched (esophagus, vagina)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (156699606 - 156705816)

Ensembl ID

ENSG00000143320  (ver. 103.38)

Orthologs

Mouse Crabp2: ENSMUSG00000004885

UniProt

P29373

neXtProt

NX_P29373

Human splice variants
Mouse splice variants

Protein structure