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Protein structure
ACTA1
Actin alpha 1, skeletal muscleACTA, NEM3
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019]
Top validated antibodies |
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| Novus Biologicals |  NB100-74340 |
26 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 23660-1-AP |
115 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| GeneTex | GTX11003 |
10 references | Monoclonal |
WB
EL
ICC
IHC
OA
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| antibodies-online | ABIN261450 |
18 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Boster Biological Technology | M02014-1 |
2 references | Monoclonal |
WB
ICC
IP
IHC
FC
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