Tissue expression
Cell line expression
Protein structure
RGS10
Regulator of G protein signaling 10Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 11163-1-AP | 3 references | Polyclonal |
WB
EL |
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Affinity Biosciences | DF4414 | Polyclonal |
WB
EL
ICC
IHC |
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Atlas Antibodies | HPA021305 | Polyclonal |
WB
IHC |
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LSBio | LS-C805325 | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | PA5-106721 | Polyclonal |
WB
ICC
IHC
|
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