Tissue expression
Cell line expression
Protein structure
SESN3
Sestrin 3MGC29667, SEST3
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Top validated antibodies |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Proteintech Group | ![]() |
10 references | Polyclonal |
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antibodies-online | ![]() |
2 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Bioss | ![]() |
1 references | Polyclonal |
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