Tissue expression
Cell line expression
Protein structure
GFRA1
GDNF family receptor alpha 1GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Top validated antibodies |
|||||
Novus Biologicals | NBP1-77043 | 2 references | Polyclonal |
WB
EL
ICC
IHC |
|
R&D Systems | AF560 | 18 references | Polyclonal |
WB
IHC
BN
|
|
antibodies-online | ABIN1449286 | 5 references | Monoclonal |
WB
IP
FC
|
|
Boster Biological Technology | A02897 | Polyclonal |
WB
EL
ICC
IHC |
||
LSBio | LS-C832593 | Polyclonal |
WB
EL
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider