Tissue expression
Cell line expression
Protein structure
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1APPL
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 12639-1-AP | 7 references | Polyclonal |
WB
EL
IP
IHC |
|
Invitrogen Antibodies | 19885-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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Boster Biological Technology | A02381 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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NovoPro Bioscience Inc. | 108041 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
FineTest Biotech | FNab00516 | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider