Tissue expression
Cell line expression
Protein structure
WDR19
WD repeat domain 19DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp
The protein encoded by this gene is a member of the WD (tryptophan-aspartic acid) repeat family, which is a large family of structurally-related proteins known to participate in a wide range of cellular processes. Each WD repeat typically contains about 40 amino acids that are usually bracketed by glycine-histidine and tryptophan-aspartic acid (WD) dipeptides. This protein contains six WD repeats, three transmembrane domains, and a clathrin heavy-chain repeat. Mutations in this gene have been described in individuals with a wide range of disorders affecting function of the cilium. These disorders are known as ciliopathies, and include Jeune syndrome, Sensenbrenner syndromes, Senior-Loken syndrome, combined or isolated nephronophthisis (NPHP), and retinitis pigmentosa (RP). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Top validated antibodies |
|||||
Invitrogen Antibodies | ![]() |
Polyclonal |
|
||
Proteintech Group | ![]() |
Polyclonal |
|
||
NovoPro Bioscience Inc. | ![]() |
Polyclonal |
|
||
FineTest Biotech | ![]() |
Polyclonal |
|
||
Biorbyt | ![]() |
Polyclonal |
|