Tissue expression
Cell line expression
Protein structure
DEDD
Death effector domain containingCASP8IP1, DEDD1, DEFT, FLDED1, KE05
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Biorbyt | orb2227764 | Polyclonal |
WB
EL
ICC
IHC |
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Proteintech Group | 10816-1-AP | 1 references | Polyclonal |
EL
IHC |
|
antibodies-online | ABIN394021 | 5 references | Monoclonal |
WB
|
|
Invitrogen Antibodies | BS-7062R | Polyclonal |
WB
EL
IHC
|
||
Cusabio Biotech Co., Ltd | CSB-PA006648ESR1HU | Polyclonal |
WB
EL
IHC
|
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