Tissue expression
Cell line expression
Protein structure
NDUFS2
NADH:ubiquinone oxidoreductase core subunit S2CI-49
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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Invitrogen Antibodies | PA5-22364 | 2 references | Polyclonal |
WB
ICC
IHC
OA |
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NSJ Bioreagents | RQ7234 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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GeneTex | GTX114924 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Atlas Antibodies | HPA055140 | Polyclonal |
WB
ICC
IHC
|
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LSBio | LS-B10858 | Polyclonal |
WB
ICC
IHC
|
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