Tissue expression
Cell line expression
Protein structure
STC1
Stanniocalcin 1STC
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
13 references | Polyclonal |
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OriGene | ![]() |
2 references | Monoclonal |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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antibodies-online | ![]() |
4 references | Polyclonal |
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R&D Systems | ![]() |
4 references | Polyclonal |
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